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Table 2 CCQ scores in subgroups (Healthy, At Risk and COPD (Stage I-III))

From: Development, validity and responsiveness of the Clinical COPD Questionnaire

     COPD  
CCQ Healthy (ex)smokers At Risk (Stage 0) Mild (Stage I) Moderate A(Stage IIA) Moderate B (Stage IIB) Severe (Stage III)
Symptom 1.5a 3.3b 1.8a,c 2.0c,d 3.1b,d 2.9,b,c
  (0.3–3.5) (1.8–5.3) (0.5–5.0) (0.8–5.3) (0.8–4.5) (1.5–4.5)
Functional 0.8a 1.4b,c 0.3a 1.4b 1.5b 2.6c
state (0.0–3.8) (0.3–6.0) (0.0–2.5) (0.3–4.0) (0.5–4.8) (2.0–5.0)
Mental state 0.0a 0.0a,b 0.0a 0.0a,c 1.0b 0.5b,c
  (0.0–3.0) (0.0–3.5) (0.0–1.0) (0.0–4.5) (0.0–5.0) (0.0–3.0)
Total 0.8a 2.0b,c 1.0a,d 1.3b,d 1.9b,c 2.5c
  (0.1–3.3) (0.8–5.2) (0.2–2.5) (0.5–4.3) (0.9–4.7) (1.7–4.3)
  1. CCQ = Clinical COPD Questionnaire; range 0 – 6; 0 indicating best possible clinical control and 6 indicating worst possible clinical control. Medians not sharing a common superscript letter (a,b,c,d) are significant different at p < 0.05 after Mann-Whitney U test. Healthy (ex) smokers; normal spirometry, no chronic symptoms (cough, sputum production). COPD classification of COPD by severity according to the GOLD guidelines; Stage 0: normal spirometry, chronic symptoms (cough, sputum production); Stage I: FEV1/FVC < 70%, FEV1 ≥ 80 % predicted, with or without chronic symptoms (cough, sputum production, dyspnea); Stage IIA: FEV1/FVC < 70%, 50% ≥ FEV1 < 80 % predicted; Stage IIB: FEV1/FVC < 70%, 30% ≥ FEV1 < 50 % predicted; Stage III: FEV1/FVC < 70%, FEV1 < 30 % predicted or FEV1 < 50% predicted plus respiratory failure or clinical signs of right heart failure.
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