| | | | |
COPD
| |
|---|
|
CCQ
|
Healthy (ex)smokers
|
At Risk (Stage 0)
|
Mild (Stage I)
|
Moderate A(Stage IIA)
|
Moderate B (Stage IIB)
|
Severe (Stage III)
|
|
Symptom
|
1.5a
|
3.3b
|
1.8a,c
|
2.0c,d
|
3.1b,d
|
2.9,b,c
|
| |
(0.3–3.5)
|
(1.8–5.3)
|
(0.5–5.0)
|
(0.8–5.3)
|
(0.8–4.5)
|
(1.5–4.5)
|
|
Functional
|
0.8a
|
1.4b,c
|
0.3a
|
1.4b
|
1.5b
|
2.6c
|
|
state
|
(0.0–3.8)
|
(0.3–6.0)
|
(0.0–2.5)
|
(0.3–4.0)
|
(0.5–4.8)
|
(2.0–5.0)
|
|
Mental state
|
0.0a
|
0.0a,b
|
0.0a
|
0.0a,c
|
1.0b
|
0.5b,c
|
| |
(0.0–3.0)
|
(0.0–3.5)
|
(0.0–1.0)
|
(0.0–4.5)
|
(0.0–5.0)
|
(0.0–3.0)
|
|
Total
|
0.8a
|
2.0b,c
|
1.0a,d
|
1.3b,d
|
1.9b,c
|
2.5c
|
| |
(0.1–3.3)
|
(0.8–5.2)
|
(0.2–2.5)
|
(0.5–4.3)
|
(0.9–4.7)
|
(1.7–4.3)
|
- CCQ = Clinical COPD Questionnaire; range 0 – 6; 0 indicating best possible clinical control and 6 indicating worst possible clinical control. Medians not sharing a common superscript letter (a,b,c,d) are significant different at p < 0.05 after Mann-Whitney U test. Healthy (ex) smokers; normal spirometry, no chronic symptoms (cough, sputum production). COPD classification of COPD by severity according to the GOLD guidelines; Stage 0: normal spirometry, chronic symptoms (cough, sputum production); Stage I: FEV1/FVC < 70%, FEV1 ≥ 80 % predicted, with or without chronic symptoms (cough, sputum production, dyspnea); Stage IIA: FEV1/FVC < 70%, 50% ≥ FEV1 < 80 % predicted; Stage IIB: FEV1/FVC < 70%, 30% ≥ FEV1 < 50 % predicted; Stage III: FEV1/FVC < 70%, FEV1 < 30 % predicted or FEV1 < 50% predicted plus respiratory failure or clinical signs of right heart failure.
