Table 1 Quality of life in gynecologic cancer research studies
From: Quality of life and psychosocial adjustment in gynecologic cancer survivors
Authors | Date | QOL assessment | Other assessments | Major findings |
|---|---|---|---|---|
Bodurka – Bevers et al. | 2000 | SF-36 | CES-D, STAI | -higher than expected prevalence of depression, anxiety |
Miller et al | 2003 | FACT-G | self-report questionnaires | 57% of patients reported needing help with needing help with |
Capelli et al | 2002 | SF-36 | None | Women with primary GYN CA had similar QOL to healthy women |
-Women with recurrent disease had significantly poorer QOL compared to healthy women | ||||
Wenzel et al. | 2002 | telephone interview | physical exam | -long term survivors of ovarian CA report good QOL compared to other cancer cohorts and healthy individuals |
-20% of individuals had significant long term treatment-related side effects | ||||
Greimel et al. | 2002 | EORTC, QL-I | KPS | -GYN CA pts have poorer QOL compared to breast CA pts during treatment |
-Both groups have comparable QOL at one year follow-up | ||||
-predictors of QOL included pre-tx KPS, severity of surgery | ||||
Miller et al. | 2002 | FACT-G | None | no differences in QOL between disease-free GYN CA pts and healthy women |
-poorest QOL in pts with ovarian CA, longer treatment | ||||
-risk factors for poor QOL included lack of education, lack of help at home | ||||
Eisemann et al | 1999 | clinical interview | non-standardized questionnaires | pts with cervical CA have more physical symptoms than pts with endometrial CA-pre-tx well-being predicted post-tx well-being |
Chan et al. | 2001 | clinical interview | HAMAS, interview | -incidence of depression in disease-free sample twice that of normal population |
-risk factors for poor QOL included lack of education, low religious belief, surgical treatment | ||||
Lutgendorf et al | 2002 | FACT-G | COPE, POMS | -sleep disturbance, anergia sexual problems most common problems |
-coping style predicted QOL (even when medical variables controlled) | ||||
-disease extent and treatment intensity did NOT predict physical well-being | ||||
-QOL improved over 1 year period, even in the absence of physical improvement | ||||
Chan et al. | 2002 | EORTC-30 | None | site and stage of disease had no impact on QOL |
-younger pts reported poorer physical health | ||||
-QOL improved after treatment ended | ||||
-strong correlation between pre- and post-tx QOL | ||||
Lutgendorf et al. | 2000 | FACT-G | COPE, POMS | -extensive treatment led to poor QOL (physical, functional, and emotional) |
-avoidant coping predicted poor QOL |