Table 2 Epidemiological background and clinical characteristics of our study population regarding the prevalence of ICU infections [due to either ABRP (N = 58) or non-ABRP (N = 57)] or not (N = 236)
ABRP infections N = 58 | Non-ABRP infections N = 57 | No infections N = 236 | P-value | |
|---|---|---|---|---|
Age, years | 66 ± 14.1 | 66.8 ± 13.7 | 65.8 ± 15.1 | 0.906 |
Sex, male (%) | 43 (74.1) | 38 (66.7) | 145 (61.4) | 0.180 |
Epidemiological background | ||||
Previous year health-status, QALY | 0.78 ± 0.13 | 0.77 ± 0.14 | 0.79 ± 0.14 | 0.973 |
Obesity | 7 (12.1) | 4 (7) | 12(5) | 0.155 |
COPD | 10 (17.2) | 12 (21.1) | 50 (21.2) | 0.815 |
Asthma | 0 (0) | 0 (0) | 4 (1.7) | 1.000 |
Coronary artery disease | 13 (22.4) | 15 (26.3) | 41 (17.4) | 0.265 |
Heart Failure | 15 (25.9) | 17 (29.8) | 65 (27.5) | 0.892 |
Atrial Fibrillation | 8 (13.8) | 4 (7) | 23 (9.7) | 0.472 |
Arterial Hypertension | 14 (24.1) | 16 (28.1) | 69 (29.3) | 0.741 |
Diabetes Mellitus | 9(15.5) | 11(19.3) | 48 (20.3) | 0.699 |
Chronic Renal Failure | 2 (3.4) | 3(5.3) | 15 (6.3) | 0.684 |
Previous stroke | 2 (3.4) | 6 (10.5) | 19 (8) | 0.405 |
Alcohol abuse | 5 (8.6) | 3 (5.3) | 9 (3.8) | 0.261 |
Admitting etiology | ||||
Medical critical illness | 37(63.8) | 42(73.7) | 166(70.3) | 0.493 |
Surgical critical illness | 21(36.2) | 15(26.3) | 70(29.7) | 0.493 |
Cardiac arrest | 7(12.1) | 8 (14) | 13 (5.5) | 0.038 |
Clinical characteristics | ||||
APACHE II on admission | 21.6 ± 4.5 | 20.6 ± 6 | 18.6 ± 7.7 | 0.006b |
Mechanical ventilation | 51 (87.9) | 50 (87.7) | 184 (78) | 0.085 |
Central line placement | 54 (93.1) | 53 (93) | 208 (88.1) | 0.364 |
ARDS | 23 (39.7) | 14 (24.6) | 39 (16.5) | < 0.001 |
MODS score27 | 4.3 ± 3.7 | 1.7 ± 2 | 1.3 ± 2 | < 0.001 |
Sepsis (without shock) | 24 (41.4) | 14 (24.6) | – | 0.047 |
Septic shock | 21 (36.2) | 9 (15.8) | – | 0.013 |
CRRT | 11 (19) | 7 (12.3) | 14 (5.9) | 0.006 |
Multiple trauma | 11 (19) | 6 (10.5) | 25 (10.6) | 0.202 |
Hemorrhagic Shock | 3 (5.2) | 3 (5.3) | 15 (6.4) | 0.918 |
Colistin administration | 52 (89.7) | 26 (45.6) | – | < 0.001 |
Glucocorticoid administration | 19 (32.8) | 12 (21.1) | 59 (25) | 0.333 |