Total (N = 192) | Low-risk (n=117) | Medium-risk (n = 63) | High-risk (n = 12) | p value | |
---|---|---|---|---|---|
Age (years) | 65 [57–73] | 60 [53–69] | 72 [66–77] | 73 [65–81] | < 0.001 |
Gender (female) | 20.3 | 23.9 | 14.3 | 16.7 | 0.292 |
Arterial hypertension | 69.3 | 58.1 | 85.7 | 91.7 | < 0.001 |
Dyslipidemia | 64.1 | 52.1 | 82.5 | 83.3 | < 0.001 |
Diabetes mellitus | 37.5 | 25.6 | 54.0 | 66.7 | < 0.001 |
COPD | 20.3 | 13.7 | 30.2 | 33.3 | 0.016 |
Chronic renal failure | 25.8 | 13.0 | 42.9 | 58.3 | < 0.001 |
Previous atrial fibrillation | 34.9 | 22.2 | 50.8 | 75.0 | < 0.001 |
LVEF | 30 [27–36] | 30 [28–36] | 30 [28–36] | 27 [25–32] | 0.116 |
Ischemic etiology | 50 | 40.2 | 65.1 | 66.7 | 0.003 |
Duration of HF (years) | 3 [2–5 | 2 [2–4] | 5 [3–7] | 6 [3–9] | < 0.001 |
Functional class | |||||
NYHA 1 | 36.1 | 44.8 | 23.8 | 16.7 | |
NYHA 2 | 47.6 | 46.6 | 52.4 | 33.3 | < 0.001 |
NYHA 3 | 16.2 | 8.6 | 23.8 | 50.0 | |
ICD/CRT | 12.0 | 5.1 | 20.6 | 33.3 | 0.001 |
Heart rate | 61 [55–70] | 60 [55–66] | 63 [60–70] | 64 [59–80] | 0.107 |
NT-proBNP (pg/mL) | 984 [393–2334] | 599 [244–1211] | 2045 [860–3664] | 3494 [1503–8541] | < 0.001 |
hs T-Troponin (ng/mL) | 15 [8–27] | 11 [6–16] | 24 [17–40] | 53 [39–68] | < 0.001 |
Glomerular filtration (mL/min/1.73 m2) | 76.07 ± 27.75 | 86.36 ± 23.66 | 62.54 ± 22.59 | 46.75 ± 38.50 | < 0.001 |
Sodium (mEq/L) | 141 [140–143] | 141 [140–143] | 142 [141–144] | 139 [138–141] | 0.005 |
ACEI/ARB | 60.4 | 62.4 | 58.7 | 50.0 | 0.667 |
ARNI | 38.0 | 35.9 | 39.7 | 50.0 | 0.598 |
Betablockers | 95.8 | 97.4 | 95.2 | 83.3 | 0.064 |
MRA | 78.1 | 76.1 | 82.5 | 75.0 | 0.584 |
Diuretics | 67.7 | 47.0 | 100.0 | 100.0 | < 0.001 |