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  1. Patients with moderate to severe malignancy-related pain frequently require the use of opioid pharmacotherapy. Unfortunately, many cancer patients continue to be prescribed subtherapeutic doses of pain medicat...

    Authors: Tracy L Skaer

    Citation: Health and Quality of Life Outcomes 2006 4:24

    Content type: Review

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  2. Persons with Irritable bowel syndrome (IBS) are seriously affected in their everyday life. The effect across different cultural settings of IBS on their quality of life has been little studied. The aim was to ...

    Authors: Åshild Faresjö, Foteini Anastasiou, Christos Lionis, Saga Johansson, Mari-Ann Wallander and Tomas Faresjö

    Citation: Health and Quality of Life Outcomes 2006 4:21

    Content type: Research

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  3. The Assessment of Quality of Life (AQoL) utility instrument was psychometrically developed for the general population. This study aimed to explore its potential as an osteoarthritis (OA) outcome measure.

    Authors: Kathryn Whitfield, Rachelle Buchbinder, Leonie Segal and Richard H Osborne

    Citation: Health and Quality of Life Outcomes 2006 4:19

    Content type: Research

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  4. The Middlesex Elderly Assessment of Mental State (MEAMS) was developed as a screening test to detect cognitive impairment in the elderly. It includes 12 subtests, each having a 'pass score'. A series of tasks ...

    Authors: Alan Tennant, Ayse A Küçükdeveci, Sehim Kutlay and Atilla H Elhan

    Citation: Health and Quality of Life Outcomes 2006 4:18

    Content type: Research

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  5. Numerous studies have identified a reduced health related quality of life (HRQL) in patients that have either diabetes or cancer. We assessed the HRQL burden in patients with these comorbid conditions, postula...

    Authors: Samantha L Bowker, Sheri L Pohar and Jeffrey A Johnson

    Citation: Health and Quality of Life Outcomes 2006 4:17

    Content type: Research

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  6. Psychometric properties of two measures of psychological well-being were evaluated for adults with growth hormone deficiency (GHD): the General Well-being Index, (GWBI) – British version of the Psychological G...

    Authors: Carolyn V McMillan, Clare Bradley, James Gibney, David L Russell-Jones and Peter H Sönksen

    Citation: Health and Quality of Life Outcomes 2006 4:16

    Content type: Research

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  7. Interpretations of profile and preference based measure scores can differ. Profile measures often use a norm-based scoring algorithm where each scale is scored to have a standardized mean and standard deviatio...

    Authors: Alison L Supina, David H Feeny, Linda J Carroll and Jeffrey A Johnson

    Citation: Health and Quality of Life Outcomes 2006 4:15

    Content type: Research

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  8. Health-Related Quality of Life (HRQOL) has received much attention in recent years. HRQOL indicators have been used to track population trends, identify health disparities, and monitor progress in achieving na...

    Authors: Yongwen Jiang and Jana Earl Hesser

    Citation: Health and Quality of Life Outcomes 2006 4:14

    Content type: Research

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  9. Lengthy questionnaires reduce data quality and impose a burden on respondents. Previous researchers proposed that a single item ("My future seems dark to me") and a 4-item component of the Beck's Hopelessness ...

    Authors: Paul SF Yip and Yin Bun Cheung

    Citation: Health and Quality of Life Outcomes 2006 4:13

    Content type: Research

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  10. "Ikigai" is culturally defined in the society of Japan as a comprehensive concept describing subjective well-being. It is considered to be related to life-satisfaction, self-esteem, morale, happiness as well a...

    Authors: Kokoro Shirai, Hiroyasu Iso, Hideki Fukuda, Yasuhiro Toyoda, Toshio Takatorige and Kozo Tatara

    Citation: Health and Quality of Life Outcomes 2006 4:12

    Content type: Research

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  11. Successful highly active antiretroviral therapy (HAART) regimens have resulted in substantial improvements in the systemic health of HIV infected persons and increased survival times. Despite increased systemi...

    Authors: Thomas D Parsons, Alyssa J Braaten, Colin D Hall and Kevin R Robertson

    Citation: Health and Quality of Life Outcomes 2006 4:11

    Content type: Research

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  12. There is evidence regarding the usefulness of psychosocial intervention to improve health related quality of life (HRQOL) in adult cancer patients. The aim of this report is to describe an integrated approach ...

    Authors: Patrizia Pugliese, Maria Perrone, Enrica Nisi, Carlo Garufi, Diana Giannarelli, Andrew Bottomley and Edmondo Terzoli

    Citation: Health and Quality of Life Outcomes 2006 4:9

    Content type: Research

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  13. Management of pain related to advanced or metastatic cancer, although the availability of several pharmacological and non-pharmacological interventions and the existence of well-known guidelines and protocols,...

    Authors: Giovanni Apolone, Oscar Bertetto, Augusto Caraceni, Oscar Corli, Franco De Conno, Roberto Labianca, Marco Maltoni, Mariaflavia Nicora, Valter Torri and Furio Zucco

    Citation: Health and Quality of Life Outcomes 2006 4:7

    Content type: Research

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  14. The Hospital Anxiety and Depression Scale (HADS) is a widely used screening tool designed as a case detector for clinically relevant anxiety and depression. Recent studies of the HADS in coronary heart disease...

    Authors: Wenru Wang, Violeta Lopez, David Thompson and Colin R Martin

    Citation: Health and Quality of Life Outcomes 2006 4:6

    Content type: Research

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  15. Female patients with cystic fibrosis (CF) have consistently poorer survival rates than males across all ages. To determine if gender differences exist in health-related quality of life (HRQOL) of adolescent pa...

    Authors: Renata Arrington-Sanders, Michael S Yi, Joel Tsevat, Robert W Wilmott, Joseph M Mrus and Maria T Britto

    Citation: Health and Quality of Life Outcomes 2006 4:5

    Content type: Research

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  16. The Child Perceptions Questionnaire for children aged 11 to 14 years (CPQ11–14) is a 37-item measure of oral-health-related quality of life (OHRQoL) encompassing four domains: oral symptoms, functional limitation...

    Authors: Aleksandra Jokovic, David Locker and Gordan Guyatt

    Citation: Health and Quality of Life Outcomes 2006 4:4

    Content type: Research

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  17. Several quality-of-life studies in patients awaiting major joint replacement have focused on the outcomes of surgery. Interest in examining patients on the elective waiting list has increased since the beginni...

    Authors: Johanna Hirvonen, Marja Blom, Ulla Tuominen, Seppo Seitsalo, Matti Lehto, Pekka Paavolainen, Kalevi Hietaniemi, Pekka Rissanen and Harri Sintonen

    Citation: Health and Quality of Life Outcomes 2006 4:3

    Content type: Research

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  18. Whereas it is established that organic pain may induce depression, it is unclear whether pain is more common in healthy subjects with depression. We assessed the prevalence of pain in premenopausal women with ...

    Authors: Jill M Hartman, Ann Berger, Karen Baker, Jacques Bolle, Daniel Handel, Andrew Mannes, Donna Pereira, Diane St Germain, Donna Ronsaville, Nina Sonbolian, Sara Torvik, Karim A Calis, Terry M Phillips and Giovanni Cizza

    Citation: Health and Quality of Life Outcomes 2006 4:2

    Content type: Research

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  19. The estimated prevalence rate of Pervasive Developmental Disorders (PDD) in children is 6 per 1.000. Parenting children who are intellectually impaired and have PDDs is known to be linked to the impaired well-...

    Authors: Hiie Allik, Jan-Olov Larsson and Hans Smedje

    Citation: Health and Quality of Life Outcomes 2006 4:1

    Content type: Research

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  20. Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functiona...

    Authors: Rebecca Holman, Nadine Weisscher, Cees AW Glas, Marcel GW Dijkgraaf, Marinus Vermeulen, Rob J de Haan and Robert Lindeboom

    Citation: Health and Quality of Life Outcomes 2005 3:83

    Content type: Research

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  21. Chronic liver diseases (CLDs) are progressive disorder which has a significant impact on the well-being of patients and leads to significant morbidity. CLDs are characterized by disturbances in physical, psych...

    Authors: Farkhondeh Sharif, Sadrollah Mohebbi, Hamid-Reza Tabatabaee, Mehdi Saberi-Firoozi and Sakineh Gholamzadeh

    Citation: Health and Quality of Life Outcomes 2005 3:81

    Content type: Research

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  22. Previous studies have evaluated the individual effects of acute myocardial infarction (AMI) and diabetes mellitus on health-related quality of life outcomes (QOL). Due to the rising incidence of these comorbid...

    Authors: Ewurabena Simpson and Louise Pilote

    Citation: Health and Quality of Life Outcomes 2005 3:80

    Content type: Research

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  23. The aim of this study was to determine the reliability, validity and responsiveness of the Restless Legs Syndrome Quality of Life questionnaire (RLSQoL) in a clinical trial setting.

    Authors: Linda Abetz, Robert Arbuckle, Richard P Allen, Elena Mavraki and Jeffrey Kirsch

    Citation: Health and Quality of Life Outcomes 2005 3:79

    Content type: Research

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  24. To evaluate the impact of osteoporosis on the patients' quality of life, particularly in the absence of fractures.

    Authors: Maria Luisa Bianchi, Maria Rosa Orsini, Silvia Saraifoger, Sergio Ortolani, Giovanni Radaelli and Simonetta Betti

    Citation: Health and Quality of Life Outcomes 2005 3:78

    Content type: Research

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  25. Patients in emergency departments show a high prevalence of substance use. Quality of life is associated with substance use as well as socioeconomic status. Little is known about quality of life in substance-a...

    Authors: Bruno Neuner, Peter M Miller, Bodo Felsmann, Edith Weiss-Gerlach, Tim Neumann, Klaus Dieter Wernecke and Claudia Spies

    Citation: Health and Quality of Life Outcomes 2005 3:77

    Content type: Research

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  26. The Health of the Nation Outcome Scales was developed to routinely measure outcomes for adults with mental illness. Comparable instruments were also developed for children and adolescents (the Health of the Na...

    Authors: Jane E Pirkis, Philip M Burgess, Pia K Kirk, Sarity Dodson, Tim J Coombs and Michelle K Williamson

    Citation: Health and Quality of Life Outcomes 2005 3:76

    Content type: Review

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  27. While falls and urinary incontinence are prevalent among older patients, who sometimes rely on proxies to provide their health information, the validity of proxy reports of concern about falls and urinary inco...

    Authors: Takahiro Higashi, Ron D Hays, Julie A Brown, Caren J Kamberg, Chau Pham, David B Reuben, Paul G Shekelle, David H Solomon, Roy T Young, Carol P Roth, John T Chang, Catherine H MacLean and Neil S Wenger

    Citation: Health and Quality of Life Outcomes 2005 3:75

    Content type: Research

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  28. Measures of multimorbidity are often applied to source data, populations or outcomes outside the scope of their original developmental work. As the development of a multimorbidity measure is influenced by the ...

    Authors: Martin Fortin, Catherine Hudon, Marie-France Dubois, José Almirall, Lise Lapointe and Hassan Soubhi

    Citation: Health and Quality of Life Outcomes 2005 3:74

    Content type: Research

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  29. Distal radius fractures are common injuries that have an increasing impact on health across the lifespan. The purpose of this study was to identify health impacts in body structure/function, activity, and part...

    Authors: Jocelyn E Harris, Joy C MacDermid and James Roth

    Citation: Health and Quality of Life Outcomes 2005 3:73

    Content type: Research

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  30. A sizable body of research has now examined the complex relationship between quality of life (QoL) and depressive disorder. Uptake of QoL research in relation to bipolar disorder (BD) has been comparatively sl...

    Authors: Erin E Michalak, Lakshmi N Yatham and Raymond W Lam

    Citation: Health and Quality of Life Outcomes 2005 3:72

    Content type: Review

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  31. The European DISABKIDS project aims to enhance the Health Related Quality of Life (HRQoL) of children and adolescents with chronic medical conditions and their families. We describe the development of the seve...

    Authors: Rolanda M Baars, Clare I Atherton, Hendrik M Koopman, Monika Bullinger and Mick Power

    Citation: Health and Quality of Life Outcomes 2005 3:70

    Content type: Research

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  32. The QUALIOST® was designed for use with the SF-36 to measure established osteoporosis-specific quality of life (QoL). The reliability (internal consistency and test-retest) and validity of the questionnaire were ...

    Authors: Christine de la Loge, Kate Sullivan, Robert Pinkney, Patrick Marquis, Christian Roux and Pierre Jean Meunier

    Citation: Health and Quality of Life Outcomes 2005 3:69

    Content type: Research

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  33. The Rhinosinusitis Disability Index (RSDI) is a validated measure of health-related quality of life (HRQL) in rhinitis. Responsiveness of the RSDI to changes in health status over time has not been described.

    Authors: Hubert Chen, Patricia P Katz, Stephen Shiboski and Paul D Blanc

    Citation: Health and Quality of Life Outcomes 2005 3:68

    Content type: Research

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  34. The Eye Allergy Patient Impact Questionnaire (EAPIQ) was developed based on a pilot study conducted in the US and focus groups with eye allergy sufferers in Europe. The purpose of this study was to present the...

    Authors: Michael Alexander, William Berger, Patricia Buchholz, John Walt, Caroline Burk, Jeff Lee, Rob Arbuckle and Linda Abetz

    Citation: Health and Quality of Life Outcomes 2005 3:67

    Content type: Research

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  35. In the last 25 years, assessment of orthopaedic intervention has become patient focused, with the development of self-completion patient-centred outcome measures. The Oxford hip score (OHS) is a joint specific...

    Authors: Vikki Wylde, Ian D Learmonth and Victoria J Cavendish

    Citation: Health and Quality of Life Outcomes 2005 3:66

    Content type: Research

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  36. The importance of evaluating the outcomes of health care from the standpoint of the patient is now widely recognized. The purpose of this study is to develop and test a Japanese version of the National Eye Ins...

    Authors: Yoshimi Suzukamo, Tetsuro Oshika, Mitsuko Yuzawa, Yoshihiro Tokuda, Atsuo Tomidokoro, Kotaro Oki, Carol M Mangione, Joseph Green and Shunichi Fukuhara

    Citation: Health and Quality of Life Outcomes 2005 3:65

    Content type: Research

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  37. In adult quality of life (QOL) research, the QOL construct appears to differ from self-rated health status. Although increased QOL continues to be recognized as an important outcome in health promotion and med...

    Authors: Keith J Zullig, Robert F Valois and J Wanzer Drane

    Citation: Health and Quality of Life Outcomes 2005 3:64

    Content type: Research

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  38. Patients with growth hormone deficiency (GHD) frequently report to suffer from an impaired Quality of Life (QoL) and growth hormone (GH) substitution is found to improve this. However, the same test may be use...

    Authors: Jan Berend Deijen, Lucia I Arwert, Joost Witlox and Madeleine L Drent

    Citation: Health and Quality of Life Outcomes 2005 3:63

    Content type: Research

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  39. Quality of life of stoma patients is increasingly being addressed in clinical trials. However, the instruments used in the majority of these studies have not been validated specifically for stoma patients. The...

    Authors: Luis Prieto, Hanne Thorsen and Kristian Juul

    Citation: Health and Quality of Life Outcomes 2005 3:62

    Content type: Research

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  40. Idiopathic pulmonary fibrosis (IPF) is a debilitating lung disease with a survival of only three to five years from the time of diagnosis. Due to a paucity of studies, large gaps remain in our understanding of...

    Authors: Jeffrey J Swigris, Anita L Stewart, Michael K Gould and Sandra R Wilson

    Citation: Health and Quality of Life Outcomes 2005 3:61

    Content type: Research

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  41. Large variations in pain and function are seen over time in subjects at risk for and with radiographic knee osteoarthritis (OA). We hypothesized that this variation may be related not only to knee OA but also ...

    Authors: Przemyslaw T Paradowski, Martin Englund, L Stefan Lohmander and Ewa M Roos

    Citation: Health and Quality of Life Outcomes 2005 3:59

    Content type: Research

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  42. The age limit for some adult asthma clinical trials has recently been lowered to 12 years. In this study we have made minor modifications to the standardised version of the adult Asthma Quality of Life Questio...

    Authors: Elizabeth F Juniper, Klas Svensson, Ann-Christin Mörk and Elisabeth Ståhl

    Citation: Health and Quality of Life Outcomes 2005 3:58

    Content type: Research

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