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  1. The purpose of this study was to evaluate the individualized and standardized quality of life (QL) and psychological distress of patients participating in a Phase I trial of the novel therapeutic reovirus (Reo...

    Authors: Linda E Carlson, Barry D Bultz and Donald G Morris

    Citation: Health and Quality of Life Outcomes 2005 3:7

    Content type: Research

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  2. Longitudinal assessments of quality of life are needed to measure changes over the course of a disease and treatment. Computer versions of quality of life instruments have increased the feasibility of obtainin...

    Authors: Karen M Gil, Heidi E Frasure, Michael P Hopkins, Eric L Jenison and Vivian E von Gruenigen

    Citation: Health and Quality of Life Outcomes 2005 3:6

    Content type: Research

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  3. The objective of this study was to develop simultaneously a new questionnaire, the Pediatric GERD Caregiver Impact Questionnaire (PGCIQ), in American English and American Spanish in order to elucidate the impa...

    Authors: Jennifer Kim, Dorothy L Keininger, Sara Becker and Joseph A Crawley

    Citation: Health and Quality of Life Outcomes 2005 3:5

    Content type: Research

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  4. The correlation between treatment satisfaction and demographic characteristics, symptoms, or health-related quality of life (HRQL) in patients with gastroesophageal reflux disease (GERD) is unknown. The object...

    Authors: Alessio Degl' Innocenti, Gordon H Guyatt, Ingela Wiklund, Diane Heels-Ansdell, David Armstrong, Carlo A Fallone, Lisa Tanser, Sander Veldhuyzen van Zanten, Samer El-Dika, Naoki Chiba, Alan N Barkun, Peggy Austin and Holger J Schünemann

    Citation: Health and Quality of Life Outcomes 2005 3:4

    Content type: Research

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  5. The objectives of this report are to review the assessment of patient-focused outcomes in pediatric orthopedic surgery, to describe a framework for identifying appropriate sets of measures, and to illustrate a...

    Authors: William Furlong, Ronald D Barr, David Feeny and Suzanne Yandow

    Citation: Health and Quality of Life Outcomes 2005 3:3

    Content type: Review

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  6. Diabetes mellitus (DM) is an important public health concern, the impact of which is increased by the high prevalence of co-existing chronic medical conditions among subjects with DM. The aims of this study we...

    Authors: Hwee-Lin Wee, Yin-Bun Cheung, Shu-Chuen Li, Kok-Yong Fong and Julian Thumboo

    Citation: Health and Quality of Life Outcomes 2005 3:2

    Content type: Research

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  7. Little is understood about the conceptual relationship of depression and quality of life (QoL). Judgments concerning both, implicitly or explicitly, involve a time perspective. The aim of this study was to tes...

    Authors: Margaret Moore, Stefan Höfer, Hannah McGee and Lena Ring

    Citation: Health and Quality of Life Outcomes 2005 3:1

    Content type: Research

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  8. Health-Related Quality of Life (HRQoL) measures are becoming increasingly used in clinical trials as primary outcome measures. Investigators are now asking statisticians for advice on how to analyse studies th...

    Authors: Stephen J Walters and Michael J Campbell

    Citation: Health and Quality of Life Outcomes 2004 2:70

    Content type: Research

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  9. Due to differences in current socio-economical situation and historically shaped values, different societies have their own concepts of high-quality life. This diversity of concepts interferes with quality of ...

    Authors: Marika Tammaru, Judit Strömpl, Kadri Maimets and Ele Hanson

    Citation: Health and Quality of Life Outcomes 2004 2:69

    Content type: Research

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  10. Various scales have been used to assess palliative outcomes. But measurement can still be problematic and core components of measures have not been identified. This study aimed to determine the relationships b...

    Authors: Irene J Higginson and Nora Donaldson

    Citation: Health and Quality of Life Outcomes 2004 2:68

    Content type: Research

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  11. The Menopause Rating Scale is a health-related Quality of Life scale developed in the early 1990s and step-by-step validated since then. No methodologically detailed work on the utility of the scale to assess ...

    Authors: Lothar AJ Heinemann, Thai DoMinh, Frank Strelow, Silvia Gerbsch, Jörg Schnitker and Hermann PG Schneider

    Citation: Health and Quality of Life Outcomes 2004 2:67

    Content type: Research

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  12. It is known that there is an increase in the prevalence of allergy and that allergic diseases have a negative impact on individuals' health-related quality of life (HRQL). However, research in this field is ma...

    Authors: Birgitta Marklund, Staffan Ahlstedt and Gun Nordström

    Citation: Health and Quality of Life Outcomes 2004 2:65

    Content type: Research

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  13. Clinicians require brief outcome measures in their busy daily practice to document global client outcomes. Based on the UK Therapy Outcome Measure, the Australian Therapy Outcome Measures were designed to capt...

    Authors: Carolyn A Unsworth, Stephen J Duckett, Dianne Duncombe, Alison Perry, Jemma Skeat and Nicholas Taylor

    Citation: Health and Quality of Life Outcomes 2004 2:64

    Content type: Research

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  14. The 12-item General Health Questionnaire (GHQ-12) is widely used as a unidimensional instrument, but factor analyses tended to suggest that it contains two or three factors. Not much is known about the usefuln...

    Authors: Fei Gao, Nan Luo, Julian Thumboo, Calvin Fones, Shu-Chuen Li and Yin-Bun Cheung

    Citation: Health and Quality of Life Outcomes 2004 2:63

    Content type: Research

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  15. Multiple instruments exist to measure dementia behaviors, but the nursing staff perspective on those behaviors and their level of burden has not been well measured. The goal of this study was to examine the ps...

    Authors: Leah Kleinman, Lori Frank, Gabrielle Ciesla, Marcia Rupnow and Henry Brodaty

    Citation: Health and Quality of Life Outcomes 2004 2:62

    Content type: Research

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  16. This study evaluated the psychometric properties of the ADDQoL-Teen, an innovative individualised, patient-centred questionnaire measuring perceived impact of diabetes mellitus on quality of life (QoL) of teen...

    Authors: Carolyn V McMillan, Rachel J Honeyford, Jessica Datta, Nicola JH Madge and Clare Bradley

    Citation: Health and Quality of Life Outcomes 2004 2:61

    Content type: Research

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  17. The typical symptoms of coronary heart disease (CHD), chest pain and breathlessness, are well-known. They are considered quite dramatic, and can thus be fairly reliably mapped by a survey. However, people migh...

    Authors: Markku PT Sumanen, Sakari B Suominen, Markku J Koskenvuo, Lauri H Sillanmäki and Kari J Mattila

    Citation: Health and Quality of Life Outcomes 2004 2:60

    Content type: Research

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  18. Modeling latent variables such as physical disability is challenging since its measurement is performed through proxies. This poses significant methodological challenges. The objective of this article is to pr...

    Authors: Ricardo Pietrobon, Marcus Taylor, Ulrich Guller, Laurence D Higgins, Danny O Jacobs and Timothy Carey

    Citation: Health and Quality of Life Outcomes 2004 2:59

    Content type: Research

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  19. With effective treatment strategies, the focus of tuberculosis (TB) management has shifted from the prevention of mortality to the avoidance of morbidity. As such, there should be an increased focus on quality...

    Authors: Carlo A Marra, Fawziah Marra, Victoria C Cox, Anita Palepu and J Mark Fitzgerald

    Citation: Health and Quality of Life Outcomes 2004 2:58

    Content type: Research

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  20. Traditional methods of measuring oral health mainly use clinical dental indices and have been complemented by oral health related quality of life (OHRQoL) measures. Most OHRQoL studies have been on adults and ...

    Authors: Sudaduang Gherunpong, Georgios Tsakos and Aubrey Sheiham

    Citation: Health and Quality of Life Outcomes 2004 2:57

    Content type: Research

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  21. Few studies have focused on the association between the sociodemographic characteristics of a patient with the change in health-related quality of life (HRQOL) following invasive coronary procedures, and the r...

    Authors: Marijke Veenstra, Kjell I Pettersen, Arnfinn Rollag and Knut Stavem

    Citation: Health and Quality of Life Outcomes 2004 2:56

    Content type: Research

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  22. The PedsQL™ Measurement Model was designed to measure health-related quality of life (HRQOL) in children and adolescents. The PedsQL™ 4.0 Generic Core Scales were developed to be integrated with the PedsQL™ Di...

    Authors: James W Varni, Sandra A Sherman, Tasha M Burwinkle, Paige E Dickinson and Pamela Dixon

    Citation: Health and Quality of Life Outcomes 2004 2:55

    Content type: Research

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  23. Services to meet adequate rehabilitation needs of elderly stroke survivors are not always provided. Indeed, since 1995, in the wake of the Quebec shift to ambulatory care, home care services, mainly those rela...

    Authors: Lise R Talbot, Chantal Viscogliosi, Johanne Desrosiers, Claude Vincent, Jacqueline Rousseau and Line Robichaud

    Citation: Health and Quality of Life Outcomes 2004 2:53

    Content type: Research

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  24. Dementia is a chronic illness associated with a progressive loss of cognitive and intellectual abilities, such as memory, judgment and abstract thinking.

    Authors: Christian K Andersen, Kim U Wittrup-Jensen, Anette Lolk, Kjeld Andersen and Per Kragh-Sørensen

    Citation: Health and Quality of Life Outcomes 2004 2:52

    Content type: Research

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  25. Many patients with several concurrent medical conditions (multimorbidity) are seen in the primary care setting. A thorough understanding of outcomes associated with multimorbidity would benefit primary care wo...

    Authors: Martin Fortin, Lise Lapointe, Catherine Hudon, Alain Vanasse, Antoine L Ntetu and Danielle Maltais

    Citation: Health and Quality of Life Outcomes 2004 2:51

    Content type: Review

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  26. The objective of this study was to demonstrate the use of the Heckman two-step method to assess and correct for bias due to missing health related quality of life (HRQL) surveys in a clinical study of acute co...

    Authors: Anne E Sales, Mary E Plomondon, David J Magid, John A Spertus and John S Rumsfeld

    Citation: Health and Quality of Life Outcomes 2004 2:49

    Content type: Research

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  27. The objective of this study was to test the primary hypothesis that parent proxy-report of pediatric health-related quality of life (HRQL) would prospectively predict pediatric healthcare costs over a two-year...

    Authors: Michael Seid, James W Varni, Darron Segall and Paul S Kurtin

    Citation: Health and Quality of Life Outcomes 2004 2:48

    Content type: Research

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  28. Primary care physicians are caring for increasing numbers of persons with comorbid chronic illness. Longitudinal information on health outcomes associated with specific chronic conditions may be particularly r...

    Authors: Elizabeth A Bayliss, Martha S Bayliss, John E Ware Jr and John F Steiner

    Citation: Health and Quality of Life Outcomes 2004 2:47

    Content type: Research

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  29. To measure the prevalence of and associations among impairments, activity limitations and participation restrictions in persons living with HIV in British Columbia to inform support and care programs, policy a...

    Authors: Melanie Rusch, Stephanie Nixon, Arn Schilder, Paula Braitstein, Keith Chan and Robert S Hogg

    Citation: Health and Quality of Life Outcomes 2004 2:46

    Content type: Research

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  30. This paper compiles data from different sources to get a first comprehensive picture of psychometric and other methodological characteristics of the Menopause Rating Scale (MRS) scale. The scale was designed a...

    Authors: Klaas Heinemann, Alexander Ruebig, Peter Potthoff, Hermann PG Schneider, Frank Strelow, Lothar AJ Heinemann and Do Minh Thai

    Citation: Health and Quality of Life Outcomes 2004 2:45

    Content type: Review

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  31. To examine the associations between vision-targeted health-related quality of life (VT-HRQ) and ocular surface parameters in patients with Sjögren's syndrome, a systemic autoimmune disease characterized by dry...

    Authors: Susan Vitale, Linda A Goodman, George F Reed and Janine A Smith

    Citation: Health and Quality of Life Outcomes 2004 2:44

    Content type: Research

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  32. Few questionnaires on outpatients' satisfaction with hospital exist. All have been constructed without giving enough room for the patient's point of view in the validation procedure. The main objective was to ...

    Authors: Isabelle Gasquet, Sylvie Villeminot, Carla Estaquio, Pierre Durieux, Philippe Ravaud and Bruno Falissard

    Citation: Health and Quality of Life Outcomes 2004 2:43

    Content type: Research

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  33. Currently there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes, including functional status. However, there are few item banks, which have been dev...

    Authors: Rebecca Holman, Robert Lindeboom, Marinus Vermeulen and Rob J de Haan

    Citation: Health and Quality of Life Outcomes 2004 2:42

    Content type: Research

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  34. The aim of this study is to validate the questionnaire ECOS-16 (Assessment of health related quality of life in osteoporosis) for the evaluation of health related quality of life (HRQoL) in post-menopausal wom...

    Authors: Xavier Badia, Adolfo Díez-Pérez, Raquel Lahoz, Luis Lizán, Xavier Nogués and Jordi Iborra

    Citation: Health and Quality of Life Outcomes 2004 2:41

    Content type: Research

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  35. Mood disorders are a major public health problem in the United States as well as globally. Less information exists however, about the health burden resulting from subsyndromal levels of depressive symptomatolo...

    Authors: Rosemarie Kobau, Marc A Safran, Matthew M Zack, David G Moriarty and Daniel Chapman

    Citation: Health and Quality of Life Outcomes 2004 2:40

    Content type: Research

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  36. The chest pain unit (CPU) has been developed to provide a rapid and accurate diagnostic assessment for patients attending hospital with acute, undifferentiated chest pain. We aimed to measure the effect of CPU...

    Authors: Steve Goodacre and Jon Nicholl

    Citation: Health and Quality of Life Outcomes 2004 2:39

    Content type: Research

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  37. Epidemiological studies have, so far, identified factors associated with increased risk for incident or progressive OA, such as age, sex, heredity, obesity, and joint injury. There is, however, a paucity of lo...

    Authors: Przemyslaw T Paradowski, Martin Englund, Ewa M Roos and L Stefan Lohmander

    Citation: Health and Quality of Life Outcomes 2004 2:38

    Content type: Research

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  38. The Self-Perception and Relationships Tool (S-PRT) is intended to be a clinically responsive and holistic assessment of patients' experience of illness and subjective Health Related Quality of Life (HRQL).

    Authors: Mark J Atkinson, Paul M Wishart, Bushra I Wasil and John W Robinson

    Citation: Health and Quality of Life Outcomes 2004 2:36

    Content type: Research

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  39. Whilst negative responses to traumatic injury have been well documented in the literature, there is a small but growing body of work that identifies posttraumatic growth as a salient feature of this experience...

    Authors: de Sales Turner and Helen Cox

    Citation: Health and Quality of Life Outcomes 2004 2:34

    Content type: Research

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  40. In 1996, the Centers for Medicare & Medicaid Services (CMS) initiated the development of the Medicare Health Outcomes Survey (HOS). It is the first national survey to measure the quality of life and functional...

    Authors: Nathaniel Jones III, Stephanie L Jones and Nancy A Miller

    Citation: Health and Quality of Life Outcomes 2004 2:33

    Content type: Commentary

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  41. Standardization of quality of life (QOL) assessment and reporting in clinical trials is an imperative issue. While English-speaking countries have led this movement in standardization, there persists to be a l...

    Authors: Mariko Naito, Takeo Nakayama and Shunichi Fukuhara

    Citation: Health and Quality of Life Outcomes 2004 2:31

    Content type: Review

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  42. Few studies have evaluated patient-reported outcomes in connection with a primary event of deep venous thrombosis, partly due to a lack of disease-specific measures. The aim here was to develop a disease-speci...

    Authors: Ewa Hedner, Jonas Carlsson, Károly R Kulich, Lennart Stigendal, Anders Ingelgård and Ingela Wiklund

    Citation: Health and Quality of Life Outcomes 2004 2:30

    Content type: Research

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  43. Whenever questionnaires are used to collect data on constructs, such as functional status or health related quality of life, it is unlikely that all respondents will respond to all items. This paper examines w...

    Authors: Rebecca Holman, Cees AW Glas, Robert Lindeboom, Aeilko H Zwinderman and Rob J de Haan

    Citation: Health and Quality of Life Outcomes 2004 2:29

    Content type: Research

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  44. Most studies of men undergoing treatment for prostate cancer examine physical symptoms as predictors of Quality of Life (QOL). However, symptoms vary by treatment modality in this population, and psychosocial ...

    Authors: Elise L Lev, Lucille Sanzero Eller, Glen Gejerman, Patricia Lane, Steven V Owen, Michele White and Njoki Nganga

    Citation: Health and Quality of Life Outcomes 2004 2:28

    Content type: Research

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