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Table 4 Cross-sectional adjusted associations of latent classes (4A) and metabolic syndrome (4B) with HRQoL domains, without and with additional adjustment for physical activity (SAPALDIA4)

From: The modifying role of physical activity in the cross-sectional and longitudinal association of health-related quality of life with physiological functioning-based latent classes and metabolic syndrome

N = 1124

General Health (GH)

Physical

Functioning (PF)

Bodily Pain (BP)

Vitality (VT)

Mental Health (MH)

 

Coefficient

(95% CI)

P-value

Coefficient (95% CI)

P-value

Coefficient

(95% CI)

P-value

Coefficient

(95% CI)

P-value

Coefficient

(95% CI)

P-value

4A. Latent classes

          

Healthy

Reference

         

At risk

−0.22 (−2.57; 2.14)

0.855

−1.01 (− 2.05; − 0.03)

0.057

− 1.39 (− 4.17; 1.40)

0.329

−0.00 (− 2.00; 2.00)

1.000

−0.30 (− 1.97; 1.16)

0.721

Unhealthy

−3.06 (− 5.51; − 0.58)

0.015

− 5.64 (− 6.98; − 4.30)

< 0.001

−9.14 (− 13.91; − 4.38)

< 0.001

− 2.50 (− 5.22; − 0.22)

0.072

− 1.10 (− 3.37; 1.16)

0.339

+ Physical Activity

Healthy

Reference

         

At risk

0.12 (− 2.28; 2.52)

0.924

− 0.73 (− 1.65; 0.18)

0.115

−1.43 (−4.26; 1.39)

0.319

− 2.50 (− 4.52; − 0.48)

0.092

0.00 (− 1.93; 1.93)

1.000

Unhealthy

− 2.64 (− 5.29; 0.00)

0.050

− 5.00 (− 6.59; − 3.41)

< 0.001

−7.82 (− 12–48; − 3.16)

0.001

− 2.50 (− 4.76–0.24)

0.030

0.00 (− 2.46; 2.46)

1.000

Physical Activity

(Sufficiently active)

4.27 (1.98; 6.56)

< 0.001

3.92 (2.50; 5.34)

< 0.001

4.27 (0.67; 7.87)

0.020

7.50 (5.28; 9.71)

< 0.001

4.00 (1.50; 6.50)

0.002

4B. Metabolic Syndrome (MetS)

No MetS

Reference

         

Yes MetS

−3.47 (−5.41; −1.54)

< 0.001

− 3.46 (−4.69; −2.22)

< 0.001

− 2.69 (−6.39; 1.01)

0.153

− 5.00 (−7.18; − 2.82)

< 0.001

− 0.21 (− 1.99; 1.57)

0.817

+ Physical Activity

Yes MetS

− 3.18 (− 5.27; − 1.08)

0.003

− 2.40 (− 3.73; − 1.08)

< 0.001

− 2.92 (− 6.23; 0.39)

0.084

−2.50 (− 4.12; − 0.88)

0.003

0.00 (−1.76; 1.76)

1.000

Physical Activity

(Sufficiently active)

4.11 (1.69; 6.53)

0.001

4.03 (2.60; 5.45)

< 0.001

5.70 (2.88: 8.52)

< 0.001

7.50 (5.32; 9.68)

< 0.001

4.00 (1.44; 6.56)

0.002

  1. CI = Confidence interval
  2. Differences in median levels were analysed with quantile regression models; a negative effect indicates a lower median score
  3. Adjusted for sex, age, education level and study area
  4. Categorized according to WHO Physical Activity Guidelines
  5. Inactive: < 150 min of MPA and < 75 VPA per week
  6. Sufficiently active: > 150 min of MPA or > 75 VPA per week.
  7. Metabolic syndrome: Any three of the following values: Blood glucose ≥5.6 mmol/L (Hba1C ≥5.7% in SAPALDIA4); waist circumference ≥ 94 cm in men & ≥80 cm in women; systolic blood pressure ≥ 130 or diastolic blood pressure ≥ 85; hdl < 1.0 mmol/L in men & < 1.3 mmol/L in women; triglycerides ≥1.7 mmol/L
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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