Fig. 2

Instruments used in the reviewed studies to measure the impact of the disease on family members/partners. ZCBS: Zarit Caregiver Burden Scale; WHOQOL: The World Health Organization Quality of Life; SF36: The Short Form (36) Health Survey; SF12: 12-item Short Form Health Survey; IOF: Impact on Family Scale; EQ-5D: Euroqol- 5 Dimension; PedsQL 2.0 FIM: PedsQL TM 2.0 Family Impact Module; DFI: Dermatitis Family Impact questionnaire; CBS: Caregiver Burden Scale; CarerQoL-7D: Care-related Quality of Life instrument-7 Dimension; BDI: Beck Depression Inventory; FDLQI: Family Dermatology Life Quality Index; CQOLC: Caregiver Quality of Life Index-Cancer; HADS: Hospital Anxiety and Depression Scale; CQOLCF: Caregiver Quality of Life Cystic Fibrosis; IES: The Impact of Event Scale; CRA: The Caregivers Reaction Assessment Scale; CES-D: Centre for Epidemiologic Studies Depression Scale; COH-QOL: City of Hope Quality of life Questionnaire: NHP: The Nottingham Health profile questionnaire; FIQ: Family Impact Questionnaire; PSQI: Pittsburgh Sleep Quality Index; PSI: The Parenting Stress Index Questionnaire; WPAI-SHP: The Work Productivity and Activity Impairment-Specific Health Problem V2.0; QoLFQ: QoL Family Questionnaire; HAMD: Hamilton Depression Scale; CGSQ: the Caregiver Strain Questionnaire. ProQOL: Professional Quality of Life; GDS: Geriatric Depression Scale; GDS-15: Geriatric Depression Scale-15; CQOLC-LT: Caregiver Quality of life index-Liver Transplantation; IADL subscale: Instrumental Activities of Daily Living; TAAQOL: TNO-AZL Questionnaire for Adult Health-Related Quality of life; CHQ-PF28: Child Health Questionnaire-Parent Form-28; SPQ: Sibling Perception Questionnaire; CHQ-CF87: Child Health Questionnaire-Child Form 87; CESD-R: Centre for Epidemiologic Studies Depression Scale (revised); CMCRD: Caring for my Child with a Juvenile Rheumatic Disease; LSRS: Lifespan Sibling Relationship scale; DOBI: Dutch Objective Burden Inventory; CHQ-PF50: Child Health Questionnaire-Parent Form 50; PECI: Parent Experience of Child Illness; WFF: Work-Family Facilitation scale; WFC scale: Work-Family Conflict scale; PedsQLTM: Pediatric Quality of Life Inventory TM; HEMOCAB: Hemophilia Associated Caregiver Burden Scale; BAS: Burden assessment Scale; BAI: Becks Anxiety Inventory; MCSI: Modified version of Caregiver Strain Index